Im not trying to be rude but its clearly you dont understand how me7 works. you put in the proper injector info and target lambda and it works (provided the info is correct) Obd1 honda are normally tuned in open loop (with a wideband you gauge and sensor you additionally need to buy) and the wideband o2 senors just logs %% error and you copy that info back into the primary fueling table. closed loop on honda is slow and is only used at part throttle, then goes open loop at full throttle. So if you have extreme temperature, elevation and/or humidity its going to screw up the fueling based off the conditions at which it was tuned. They have no fuelling adaptation, no knock correction nothing. Honda ecus have 2 main tables they run off of or 4 if vtec they are stupid idk if its s300, hts, neptune whatever. A proper tuned me7 car will run optimum dam near any place geographically vs honda that will need to be retuned depending on climate conditions and elevation. Long story short youre comparing a grapefruit to a basketball. Ive tuned both and I can honestly tell you with me7 NOOB shortcomings   (Winols, finding maps, german acronyms,  logger, incomplete defs, etc) its well worth it in the long run. Additionally, your car comes factory equipped with a 3 port boost controller and closed loop pid boost control. Also, for esse of tuning if  you wanted to you can always wideband swap the car. Youll need to run 2 wires to the big ecu plug, swap ecus to a wideband one. Choice is yours.

AI to tune PIDs though is definitely more common now. Not specific to ME7, but rather modern control systems, from autonomous vehicles, to drones, to manufacturing robots.... just about all control systems (which started as hand tuned PIDs) are being trained with gigantic datasets.

ME7 PID is easy to fix if you use prj's feedforward approach.

A lot of initial engine calibration already on MED17 was done fully automatically on the engine dyno with a computer driving the engines, recording data and filling tables...