What are you trying to accomplish with the S6 file?
The injectors are different, the intake flaps are different, the MAF is different and so on.
You can't just flash the S6 6 spd in there, it won't work properly.
This guy knows.
I use the S6 file as a base, mainly because I have been for a long time. There are a TON of calibration differences, and even more code changes if you want it to run properly. The 4D0907559E is the S6 file you're after.