I have an ME7.5 out of a 2001 Audi TT, I've used NefMoto in the past in boot mode to read/write fine. I re-installed Windows on this machine some time ago and it stopped working. Checked another machine as well and it doesn't work no matter the baud.

It logs this every time and at every baud:

I've got 12V on 3, 21, 62, 121
Ground on 1 or 2 (do you need to ground both? I've only ever grounded one of them and I know it's worked before. I did try both at one point and same result)
I'm using an electronics power supply that I have used fine in the past that outputs exactly 12.0V

I am able to use me7_95040.exe to read/write the eeprom in boot mode and that works fine.

Pulling my hair out here.. Any suggestions?

I could be completely off my rocker, but I thought bootmode actually kinda worked in Nefmoto? I swore I've used it in the past.

I actually tried using Galetto 1260 also. It says it writes the bin file (in bootmode) and I can read the ECU and what it reads matches but when I cycle the ECU, I can't connect to it in KWP mode after that nor will it start the car. It's like the ECU is just dead. Even writing a bone stock image to it doesn't make it respond. I am too chicken to try my other working ECU for fear the same thing will happen to it.

It is limited to telling you if the ecu is in bootmode or not. That's it.